Cefonicid Sodium

Tier C — Watch / trade

Cefonicid Sodium

Originator

2001

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：PBPs

Brand：Monocid

Indications (approved)：Bacterial infection

Regional status

Withdrawn

China

Approved

2001-12-17

Japan

Synthetic routes & intermediates5 routes

Originator routes × 1Optimised (non-patent) × 4Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 2Steps 4 · Total yield /

Cefonicid-016957-68-6Cefonicid-017—Cefonicid-01261270-71-1Cefonicid-01529169-64-0Cefonicid-018159276-97-8API · Cefonicid Sodium

Code	CAS No.	Intermediate
Cefonicid-016	957-68-6	(6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-017	-	Bis(sodium)bis[(5-sulfanyl-1H-tetrazol-1-yl)methanesulfonate]
Cefonicid-012	61270-71-1	(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-015	29169-64-0	Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride
Cefonicid-018	159276-97-8	(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine

OptimisedRoute 1Steps 8 · Total yield 13.5g（Cefonicid Sodium）

Cefonicid-00113881-91-9Cefonicid-00285-44-9Cefonicid-003250654-34-3Cefonicid-00461271-03-2Cefonicid-005—Cefonicid-006—Cefonicid-007—Cefonicid-008—Cefonicid-009—Cefonicid-010751425-57-7Cefonicid-011957-68-6Cefonicid-01261270-71-1Cefonicid-01340512-60-5Cefonicid-01451818-85-0Cefonicid-01529169-64-0API · Cefonicid Sodium

Code	CAS No.	Intermediate
Cefonicid-001	13881-91-9	aminomethanesulfonic acid
Cefonicid-002	85-44-9 Available	Phthalic anhydride
Cefonicid-003	250654-34-3	(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methanesulfonic acid
Cefonicid-004	61271-03-2	(1,3-dioxoisoindol-2-yl)methanesulfonyl chloride
Cefonicid-005	-	(5-sulfanyl-1H-1,2,3,4-tetrazol-1-yl)methanesulfonic acid
Cefonicid-006	-	N-tert-butyl-1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methanesulfonamide
Cefonicid-007	-	1-amino-N-tert-butylmethanesulfonamide
Cefonicid-008	-	N-tert-butyl-1-{[(methylsulfanyl)methanethioyl]amino}methanesulfonamide
Cefonicid-009	-	N-tert-butyl-1-(5-sulfanyl-1H-1,2,3,4-tetrazol-1-yl)methanesulfonamide
Cefonicid-010	751425-57-7	{[(methylsulfanyl)methanethioyl]amino}methanesulfonic acid
Cefonicid-011	957-68-6	(6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-012	61270-71-1	(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-013	40512-60-5	(1R)-2-Chloro-2-oxo-1-phenylethyl dichloroacetate
Cefonicid-014	51818-85-0	(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-015	29169-64-0	Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride

OptimisedRoute 3Steps 3 · Total yield 170kg（Cefonicid Sodium）

Cefonicid-019145125-45-7Cefonicid-02061270-58-4Cefonicid-01261270-71-1Cefonicid-01529169-64-0API · Cefonicid Sodium

Code	CAS No.	Intermediate
Cefonicid-019	145125-45-7	(6R,7R)-7-[[(2R)-2-(Formyloxy)-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-020	61270-58-4	(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-012	61270-71-1	(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefonicid-015	29169-64-0	Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride

OptimisedRoute 4Steps 4 · Total yield 170kg（Cefonicid Sodium）

Cefonicid-021613-90-1Cefonicid-022611-73-4Cefonicid-023611-71-2Cefonicid-02429169-63-9Cefonicid-01529169-64-0API · Cefonicid Sodium

Code	CAS No.	Intermediate
Cefonicid-021	613-90-1	Oxo(phenyl)acetonitrile
Cefonicid-022	611-73-4	2-Oxo-2-phenylacetic acid
Cefonicid-023	611-71-2	(2R)-Hydroxy(phenyl)acetic acid
Cefonicid-024	29169-63-9	(2R)-(Formyloxy)(phenyl)acetic acid
Cefonicid-015	29169-64-0	Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride

OptimisedRoute 5Steps 1 · Total yield /

Cefonicid-025—Cefonicid-023611-71-2API · Cefonicid Sodium

Code	CAS No.	Intermediate
Cefonicid-025	-	Hydroxy(phenyl)acetonitrile
Cefonicid-023	611-71-2	D-Mandelic acid

Frequently asked questions

What are the approved indications of Cefonicid Sodium?

Approved indications include: Bacterial infection.

When does the Cefonicid Sodium patent expire?

No public expiry year is available for Cefonicid Sodium yet; this page updates once verified.

How many synthesis routes are recorded for Cefonicid Sodium?

5 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Cefonicid Sodium intermediates?

1 intermediate CAS of Cefonicid Sodium are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Cefonicid Sodium intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29