Pradigastat
Tier C — Watch / tradePradigastat
Targets：DGAT1
Indications (approved)：Constipation, I型高脂蛋白血症, Hypertriglyceridaemia, Coronary artery lesion, Hepatitis C, Non-alcoholic steatohepatitis, Hepatic function decline, Renal impairment
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PRAD-001 | 105640-07-1 | 4-(4-hydroxyphenyl)cyclohexan-1-one |
| PRAD-002 | 5927-18-4Available | methyl 2-(dimethoxyphosphoryl)acetate |
| PRAD-003 | 701232-66-8 | methyl 2-(4-(4-hydroxyphenyl)cyclohexylidene)acetate |
| PRAD-004 | 701232-67-9 | methyl 2-((1r,4r)-4-(4-hydroxyphenyl)cyclohexyl)acetate |
| PRAD-005 | 701232-68-0 | methyl 2-((1r,4r)-4-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)cyclohexyl)acetate |
| PRAD-006 | 73183-34-3Available | 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2-dioxaborolane) |
| PRAD-007 | 701232-69-1 | methyl 2-((1r,4r)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclohexyl)acetate |
| PRAD-008 | 624-28-2 | 2,5-dibromopyridine |
| PRAD-009 | 956136-96-2 | methyl 2-((1r,4r)-4-(4-(5-bromopyridin-2-yl)phenyl)cyclohexyl)acetate |
| PRAD-010 | 106877-33-2 | 6-(trifluoromethyl)pyridin-3-amine |
| PRAD-011 | 956136-97-3 | methyl 2-((1r,4r)-4-(4-(5-((6-(trifluoromethyl)pyridin-3-yl)amino)pyridin-2-yl)phenyl)cyclohexyl)acetate |
Frequently asked questions
What are the approved indications of Pradigastat?
Approved indications include: Constipation, I型高脂蛋白血症, Hypertriglyceridaemia, Coronary artery lesion, Hepatitis C, Non-alcoholic steatohepatitis, Hepatic function decline, Renal impairment.
When does the Pradigastat patent expire?
No public expiry year is available for Pradigastat yet; this page updates once verified.
How many synthesis routes are recorded for Pradigastat?
1 synthesis routes are recorded; the shortest is 7 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Pradigastat intermediates?
2 intermediate CAS of Pradigastat are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Pradigastat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-21