Vociprotafib
Tier C — Watch / tradeVociprotafib
Targets：SHP2
Indications (approved)：Non-small cell lung cancer, Solid tumour, Colorectal cancer, Pancreatic cancer, Metastatic cancer
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| RMC-4630-001 | 78-90-0 | propane-1,2-diamine |
| RMC-4630-002 | 609-09-6 | diethyl 2-oxomalonate |
| RMC-4630-003 | 141872-22-2 | ethyl 3-hydroxy-5-methylpyrazine-2-carboxylate |
| RMC-4630-004 | 1269026-22-3 | ethyl 6-bromo-3-hydroxy-5-methylpyrazine-2-carboxylate |
| RMC-4630-005 | 2091009-80-0 | ethyl 6-bromo-3-chloro-5-methylpyrazine-2-carboxylate |
| RMC-4630-006 | 1801766-78-8 | tert-butyl (3S,4S)-4-(((R)-tert-butylsulfinyl)amino)-3-methyl-2-oxa-8-azaspiro[4.5]decane-8-carboxylate |
| RMC-4630-007 | 1801767-25-8 | (3S,4S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine |
| RMC-4630-008 | 2172654-34-9 | ethyl 3-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-6-bromo-5-methylpyrazine-2-carboxylate |
| RMC-4630-009 | 2172654-35-0 | (3-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-6-bromo-5-methylpyrazin-2-yl)methanol |
| RMC-4630-010 | 1017793-21-3 | 4-bromo-3-chloro-2-fluoropyridine |
| RMC-4630-011 | 861024-02-4 | 4-bromo-3-chloropyridin-2-amine |
| RMC-4630-012 | 50448-95-8 | 2-ethylhexyl 3-mercaptopropanoate |
| RMC-4630-013 | 2172653-16-4 | 2-ethylhexyl 3-((2-amino-3-chloropyridin-4-yl)thio)propanoate |
| RMC-4630-014 | 2055759-39-0 | 2-amino-3-chloropyridine-4-thiol |
Frequently asked questions
What are the approved indications of Vociprotafib?
Approved indications include: Non-small cell lung cancer, Solid tumour, Colorectal cancer, Pancreatic cancer, Metastatic cancer.
When does the Vociprotafib patent expire?
No public expiry year is available for Vociprotafib yet; this page updates once verified.
How many synthesis routes are recorded for Vociprotafib?
1 synthesis routes are recorded; the shortest is 10 steps with 26 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vociprotafib intermediates?
All intermediates in Vociprotafib routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Vociprotafib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-07