Ipatasertib
Tier C — Watch / tradeIpatasertib
Targets：AKT1
Indications (approved)：Breast cancer, 三阴性乳腺癌, Castration-resistant prostate cancer, Prostate cancer, Peritoneal cancer, Ovarian cancer, Genitourinary neoplasm, Female reproductive system cancer
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| IPAT-001 | 25026-34-0 | 2-(4-chlorophenyl)acetyl chloride |
| IPAT-002 | 102029-44-7Available | (R)-4-benzyloxazolidin-2-one |
| IPAT-003 | 220041-96-3 | (R)-4-benzyl-3-(2-(4-chlorophenyl)acetyl)oxazolidin-2-one |
| IPAT-004 | 1189324-78-4 | tert-butyl isopropyl(methoxymethyl)carbamate |
| IPAT-005 | 1396256-89-5 | tert-butyl ((S)-3-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl)(isopropyl)carbamate |
| IPAT-006 | 1001179-33-4 | (S)-3-((tert-butoxycarbonyl)(isopropyl)amino)-2-(4-chlorophenyl)propanoic acid |
| IPAT-007 | 1001269-85-7 | (5R,7R)-5-methyl-4-(piperazin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol dihydrochloride |
| IPAT-008 | 1001270-64-9 | tert-butyl ((S)-2-(4-chlorophenyl)-3-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-oxopropyl)(isopropyl)carbamate |
| Ipatasertib Dihydrochloride | 1001264-89-6 | (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one dihydrochloride |
Frequently asked questions
What are the approved indications of Ipatasertib?
Approved indications include: Breast cancer, 三阴性乳腺癌, Castration-resistant prostate cancer, Prostate cancer, Peritoneal cancer, Ovarian cancer, Genitourinary neoplasm, Female reproductive system cancer.
When does the Ipatasertib patent expire?
No public expiry year is available for Ipatasertib yet; this page updates once verified.
How many synthesis routes are recorded for Ipatasertib?
1 synthesis routes are recorded; the shortest is 5 steps with 2.1 g (Ipatasertib Dihydrochloride) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Ipatasertib intermediates?
1 intermediate CAS of Ipatasertib are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Ipatasertib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-09