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Lanifibranor

Tier C — Watch / trade

Lanifibranor

AbbVie
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:PPARγ, PPARα, PPARδ

Indications (approved):Non-alcoholic steatohepatitis, Type 2 diabetes, 弥漫性硬皮病

Regional status

US
Phase III
2021-08-19
EU
Phase III
2021-08-19
China
Phase III
2021-08-19
Japan
-

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield /
IVA-337-00163069-48-7IVA-337-002181124-40-3IVA-337-0032186707-15-1IVA-337-00477758-51-1IVA-337-005927961-17-9API · Lanifibranor
CodeCAS No.Intermediate
IVA-337-00163069-48-7Available4-chloro-2-iodoaniline
IVA-337-002181124-40-3Availablebenzo[d]thiazole-6-sulfonyl chloride
IVA-337-0032186707-15-1AvailableN-(4-chloro-2-iodophenyl)benzo[d]thiazole-6-sulfonamide
IVA-337-00477758-51-1Availablemethyl hex-5-ynoate
IVA-337-005927961-17-9Availablemethyl 4-(1-(benzo[d]thiazol-6-ylsulfonyl)-5-chloro-1H-indol-2-yl)butanoate
OptimisedRoute 2Steps 5 · Total yield /
IVA-337-006160938-18-1IVA-337-007927962-39-8IVA-337-008927962-42-3IVA-337-009927963-07-3API · Lanifibranor
CodeCAS No.Intermediate
IVA-337-006160938-18-1Available4-chloro-2-iodo-1-nitrobenzene
IVA-337-007927962-39-8Availablemethyl 6-(5-chloro-2-nitrophenyl)hex-5-ynoate
IVA-337-008927962-42-3Availablemethyl 6-(2-amino-5-chlorophenyl)hex-5-ynoate
IVA-337-009927963-07-3Availablemethyl 6-(2-(benzo[d]thiazole-6-sulfonamido)-5-chlorophenyl)hex-5-ynoate

Frequently asked questions

What are the approved indications of Lanifibranor?

Approved indications include: Non-alcoholic steatohepatitis, Type 2 diabetes, 弥漫性硬皮病.

When does the Lanifibranor patent expire?

No public expiry year is available for Lanifibranor yet; this page updates once verified.

How many synthesis routes are recorded for Lanifibranor?

2 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Lanifibranor intermediates?

9 intermediate CAS of Lanifibranor are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Lanifibranor intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-06