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Namodenoson

Tier C — Watch / trade

Namodenoson

National Institutes of Health (NIH)
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:ADORA3

Indications (approved):Hepatocellular carcinoma, Liver cirrhosis, Non-alcoholic steatohepatitis, Pancreatic cancer, Chronic hepatitis C

Regional status

US
Phase III
2023-03-15
EU
Phase III
2023-03-15
China
Phase III
2025-08-19
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 11 · Total yield 13.4 mg
NAMOD-00113039-63-9NAMOD-0021628567-06-5NAMOD-003—NAMOD-004—NAMOD-005—NAMOD-006—NAMOD-007—NAMOD-008—NAMOD-009120046-86-8NAMOD-010163042-90-8NAMOD-0115451-40-1NAMOD-0123718-88-5Namodenoson163042-96-4API · Namodenoson
CodeCAS No.Intermediate
NAMOD-00113039-63-9(2R,3S,4R)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol
NAMOD-0021628567-06-5(2R,3S,4R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-methoxytetrahydrofuran-3,4-diol
NAMOD-003-(2R,3R,4R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-methoxytetrahydrofuran-3,4-diyl dibenzoate
NAMOD-004-(2R,3R,4R)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diyl dibenzoate
NAMOD-005-(2S,3S,4R)-3,4-bis(benzoyloxy)-5-methoxytetrahydrofuran-2-carboxylic acid
NAMOD-006-(3R,4S,5S)-2-methoxy-5-(methoxycarbonyl)tetrahydrofuran-3,4-diyl dibenzoate
NAMOD-007-(3R,4S,5S)-2-methoxy-5-(methylcarbamoyl)tetrahydrofuran-3,4-diyl dibenzoate
NAMOD-008-(3R,4S,5S)-2-acetoxy-5-(methylcarbamoyl)tetrahydrofuran-3,4-diyl dibenzoate
NAMOD-009120046-86-82-chloro-N-(3-iodobenzyl)-9H-purin-6-amine
NAMOD-010163042-90-8(2R,3R,4S,5S)-2-(2-chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-5-(methylcarbamoyl)tetrahydrofuran-3,4-diyl dibenzoate
NAMOD-0115451-40-12,6-dichloro-9H-purine
NAMOD-0123718-88-5(3-iodophenyl)methanamine hydrochloride
Namodenoson163042-96-4-

Frequently asked questions

What are the approved indications of Namodenoson?

Approved indications include: Hepatocellular carcinoma, Liver cirrhosis, Non-alcoholic steatohepatitis, Pancreatic cancer, Chronic hepatitis C.

When does the Namodenoson patent expire?

No public expiry year is available for Namodenoson yet; this page updates once verified.

How many synthesis routes are recorded for Namodenoson?

1 synthesis routes are recorded; the shortest is 11 steps with 13.4 mg total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Namodenoson intermediates?

All intermediates in Namodenoson routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Namodenoson intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-03