← Back to patent-cliff list

Sulforafan alfadex

Tier C — Watch / trade

Sulforafan alfadex

Pharmagra Labs Inc
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:Nrf2, AR, Wingless type MMTV integration site family protein, HDAC, SHH

Brand:Sulforadex

Indications (approved):Kidney disease, Chronic renal impairment, Parkinson's disease, Schizophrenia, Lung cancer, 自闭症, 自闭症谱系障碍, 鼻唇沟皱纹

Regional status

US
Phase II
2010-11-01
EU
No progress
2016-04-01
China
Phase II
2020-08-31
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 5 · Total yield 12.14 g (Sulforadex)
Sulforadex4478-93-7SULFORA-0011074-82-4SULFORA-002110-52-1SULFORA-0035394-18-3SULFORA-00452096-68-1SULFORA-005163956-72-7SULFORA-006187587-70-8API · Sulforafan alfadex
CodeCAS No.Intermediate
Sulforadex4478-93-7-
SULFORA-0011074-82-4potassium 1,3-dioxoisoindolin-2-ide
SULFORA-002110-52-1Available1,4-dibromobutane
SULFORA-0035394-18-32-(4-bromobutyl)isoindoline-1,3-dione
SULFORA-00452096-68-1-
SULFORA-005163956-72-7-
SULFORA-006187587-70-8-

Frequently asked questions

What are the approved indications of Sulforafan alfadex?

Approved indications include: Kidney disease, Chronic renal impairment, Parkinson's disease, Schizophrenia, Lung cancer, 自闭症, 自闭症谱系障碍, 鼻唇沟皱纹.

When does the Sulforafan alfadex patent expire?

No public expiry year is available for Sulforafan alfadex yet; this page updates once verified.

How many synthesis routes are recorded for Sulforafan alfadex?

1 synthesis routes are recorded; the shortest is 5 steps with 12.14 g (Sulforadex) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Sulforafan alfadex intermediates?

1 intermediate CAS of Sulforafan alfadex are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Sulforafan alfadex intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-21