JNJ-54175446
Tier C — Watch / tradeJNJ-54175446
Targets：P2RX7
Indications (approved)：Major depressive disorder, Inflammatory disease
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| JNJ-54175446-001 | 23056-35-1 | 4-chloro-2-methyl-3-nitropyridine |
| JNJ-54175446-002 | 1683-85-8 | 5-fluoropyrimidin-2-amine |
| JNJ-54175446-003 | 1627902-13-9 | 5-fluoro-N-(2-methyl-3-nitropyridin-4-yl)pyrimidin-2-amine |
| JNJ-54175446-004 | 2102395-60-6 | N4-(5-fluoropyrimidin-2-yl)-2-methylpyridine-3,4-diamine |
| JNJ-54175446-005 | 2097603-70-6 | 1-(5-fluoropyrimidin-2-yl)-4-methyl-1H-[1,2,3]triazolo[4,5-c]pyridine |
| JNJ-54175446-006 | 2097603-71-7 | 1-(5-fluoropyrimidin-2-yl)-4-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine |
| JNJ-54175446-007 | 39226-97-6 | 2-chloro-3-(trifluoromethyl)benzoic acid |
| JNJ-54175446-008 | 1627902-12-8 | (2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyrimidin-2-yl)-4-methyl-1,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)methanone |
Frequently asked questions
What are the approved indications of JNJ-54175446?
Approved indications include: Major depressive disorder, Inflammatory disease.
When does the JNJ-54175446 patent expire?
No public expiry year is available for JNJ-54175446 yet; this page updates once verified.
How many synthesis routes are recorded for JNJ-54175446?
1 synthesis routes are recorded; the shortest is 6 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy JNJ-54175446 intermediates?
All intermediates in JNJ-54175446 routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for JNJ-54175446 intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-07