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Basmisanil

Tier C — Watch / trade

Basmisanil

F. Hoffmann-La Roche
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:GABRA5

Indications (approved):Dup15q综合征, Stroke, 唐氏综合征, Schizophrenia

Regional status

US
Phase II
2014-05-05
EU
Discontinued
2014-05-05
China
-
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 7 · Total yield 28.9 g
BASM-001459-57-4BASM-002459-23-4BASM-00342202-95-9BASM-0042723-42-4BASM-005954230-39-8BASM-0061018297-63-6BASM-00733252-28-7BASM-0081431329-33-7BASM-0091159600-32-4BASM-01039093-93-1Basmisanil1159600-41-5API · Basmisanil
CodeCAS No.Intermediate
BASM-001459-57-44-fluorobenzaldehyde
BASM-002459-23-4(E)-4-fluorobenzaldehyde oxime
BASM-00342202-95-9(Z)-4-fluoro-N-hydroxybenzimidoyl chloride
BASM-0042723-42-4ethyl (Z)-3-(pyrrolidin-1-yl)but-2-enoate
BASM-005954230-39-8ethyl 3-(4-fluorophenyl)-5-methylisoxazole-4-carboxylate
BASM-0061018297-63-6(3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methanol
BASM-00733252-28-76-chloronicotinonitrile
BASM-0081431329-33-76-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)nicotinonitrile
BASM-0091159600-32-46-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)nicotinic acid
BASM-01039093-93-1Availablethiomorpholine 1,1-dioxide
Basmisanil1159600-41-5(1,1-dioxidothiomorpholino)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone

Frequently asked questions

What are the approved indications of Basmisanil?

Approved indications include: Dup15q综合征, Stroke, 唐氏综合征, Schizophrenia.

When does the Basmisanil patent expire?

No public expiry year is available for Basmisanil yet; this page updates once verified.

How many synthesis routes are recorded for Basmisanil?

1 synthesis routes are recorded; the shortest is 7 steps with 28.9 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Basmisanil intermediates?

1 intermediate CAS of Basmisanil are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Basmisanil intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-12