Varoglutamstat
Tier C — Watch / tradeVaroglutamstat
Targets：Glutaminyl-peptide cyclotransferase
Indications (approved)：Dementia, Mild cognitive impairment, Alzheimer's disease
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PQ-912 | - | - |
| PQ-912-001 | 5736-85-6 | 4-propoxybenzaldehyde |
| PQ-912-002 | 80122-67-4 | 1-propoxy-4-vinylbenzene |
| PQ-912-003 | 1276021-73-8 | (S)-tert-butyl (2-hydroxy-1-(4-propoxyphenyl)ethyl)carbamate |
| PQ-912-004 | - | (S)-2-((tert-butoxycarbonyl)amino)-2-(4-propoxyphenyl)ethyl 4-methylbenzenesulfonate |
| PQ-912-005 | - | (S)-tert-butyl (2-azido-1-(4-propoxyphenyl)ethyl)carbamate |
| PQ-912-006 | - | (S)-tert-butyl (2-((4-methoxybenzyl)amino)-1-(4-propoxyphenyl)ethyl)carbamate |
| PQ-912-007 | 1276021-70-5 | (S)-1-(4-methoxybenzyl)-4-(4-propoxyphenyl)imidazolidin-2-one |
| PQ-912-008 | 21304-38-1 | 4-iodobenzene-1,2-diamine |
| PQ-912-009 | 1276021-71-6 | (S)-3-(3,4-diaminophenyl)-1-(4-methoxybenzyl)-4-(4-propoxyphenyl)imidazolidin-2-one |
Frequently asked questions
What are the approved indications of Varoglutamstat?
Approved indications include: Dementia, Mild cognitive impairment, Alzheimer's disease.
When does the Varoglutamstat patent expire?
No public expiry year is available for Varoglutamstat yet; this page updates once verified.
How many synthesis routes are recorded for Varoglutamstat?
1 synthesis routes are recorded; the shortest is 8 steps with 35 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Varoglutamstat intermediates?
All intermediates in Varoglutamstat routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Varoglutamstat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-11