18-Methoxycoronaridine
Tier C — Watch / trade18-Methoxycoronaridine
Targets：nAChRα3&β4
Indications (approved)：利什曼原虫感染, Drug-related adverse effects and reactions, Opioid dependence
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| 18-MC-001 | - | methyl 3-((R)-1-(naphthalen-1-yl)ethyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole-5-carboxylate |
| 18-MC-002 | 188125-30-6 | 4-(1,3-dioxolan-2-yl)-6-methoxyhexanal |
| 18-MC-003 | 341970-89-6 | methyl (3aS,4R,11bR)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate |
| 18-MC-004 | - | methyl (3aR,4S,11bS)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate |
| 18-MC-005 | - | methyl 5-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole-7-carboxylate |
| 18-MC-006 | 247088-80-8 | methyl (5R,7R)-5-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole-7-carboxylate |
| 18-MC-007 | - | methyl (7S,9R)-5-(2-methoxyethyl)-1,6,7,8,9,10-hexahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indole-9-carboxylate |
| Code | CAS No. | Intermediate |
|---|---|---|
| 18-MC-008 | - | - |
| 18-MC-009 | - | - |
| 18-MC-010 | 341970-92-1 | methyl (3aS,4R,11bR)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate |
| 18-MC-011 | 188125-38-4 | methyl (3aS,4R,11bR)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-benzyl-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate |
Frequently asked questions
What are the approved indications of 18-Methoxycoronaridine?
Approved indications include: 利什曼原虫感染, Drug-related adverse effects and reactions, Opioid dependence.
When does the 18-Methoxycoronaridine patent expire?
No public expiry year is available for 18-Methoxycoronaridine yet; this page updates once verified.
How many synthesis routes are recorded for 18-Methoxycoronaridine?
2 synthesis routes are recorded; the shortest is 3 steps with 0.51 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy 18-Methoxycoronaridine intermediates?
All intermediates in 18-Methoxycoronaridine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for 18-Methoxycoronaridine intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-06