Resiquimod

Tier C — Watch / trade

Resiquimod

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：TLR7, TLR8

Indications (approved)：Bladder cancer, Melanoma, Cutaneous T-cell lymphoma

Regional status

Phase II

2010-05-20

No progress

2017-12-19

China

Japan

Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 7 · Total yield 1.5 g (CD-11301)

CD-11301-00186-95-3CD-11301-00215151-57-2CD-11301-003132521-66-5CD-11301-0042854-16-2CD-11301-00533860-77-2CD-11301-006133860-78-3CD-11301-00714077-58-8CD-11301-008253120-65-9CD-11301-009558-30-5API · Resiquimod

Code	CAS No.	Intermediate
CD-11301-001	86-95-3	quinoline-2,4-diol
CD-11301-002	15151-57-2	3-nitroquinoline-2,4-diol
CD-11301-003	132521-66-5	2,4-dichloro-3-nitroquinoline
CD-11301-004	2854-16-2	1-amino-2-methylpropan-2-ol
CD-11301-005	33860-77-2	1-((2-chloro-3-nitroquinolin-4-yl)amino)-2-methylpropan-2-ol
CD-11301-006	133860-78-3	1-((3-amino-2-chloroquinolin-4-yl)amino)-2-methylpropan-2-ol
CD-11301-007	14077-58-8	2-ethoxyacetyl chloride
CD-11301-008	253120-65-9	N-(2-chloro-4-((2-hydroxy-2-methylpropyl)amino)quinolin-3-yl)-2-ethoxyacetamide
CD-11301-009	558-30-5	2,2-dimethyloxirane

Frequently asked questions

What are the approved indications of Resiquimod?

Approved indications include: Bladder cancer, Melanoma, Cutaneous T-cell lymphoma.

When does the Resiquimod patent expire?

No public expiry year is available for Resiquimod yet; this page updates once verified.

How many synthesis routes are recorded for Resiquimod?

1 synthesis routes are recorded; the shortest is 7 steps with 1.5 g (CD-11301) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Resiquimod intermediates?

All intermediates in Resiquimod routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Resiquimod intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-21