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Basimglurant Sulfate

Tier C — Watch / trade

Basimglurant Sulfate

F. Hoffmann-La Roche
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
-
Type

Targets:mGluR5

Indications (approved):三叉神经痛, Tuberous sclerosis, 脆性X染色体综合征, Major depressive disorder, Depression

Regional status

US
Phase III
2022-01-11
EU
Phase III
2022-01-11
China
-
Japan
No progress
2011-10-01

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 6 · Total yield 69 g
BASI-001141-97-9BASI-0025408-04-8BASI-003371-40-4BASI-004—BASI-0051651165-01-3BASI-0063678-62-4BASI-0071651165-03-5BASI-0083724-43-4BASI-0091651165-06-8API · Basimglurant Sulfate
CodeCAS No.Intermediate
BASI-001141-97-9Availableethyl 3-oxobutanoate
BASI-0025408-04-8ethyl (E)-2-(hydroxyimino)-3-oxobutanoate
BASI-003371-40-4Available4-fluoroaniline
BASI-004-ethyl (E)-3-((4-fluorophenyl)imino)-2-nitrobutanoate
BASI-0051651165-01-3ethyl 1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxylate
BASI-0063678-62-42-chloro-4-methylpyridine
BASI-0071651165-03-52-(2-chloropyridin-4-yl)-1-(1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-yl)ethan-1-one
BASI-0083724-43-4AvailableN-(chloromethylene)-N-methylmethanaminium chloride
BASI-0091651165-06-8(E)-3-chloro-2-(2-chloropyridin-4-yl)-3-(1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-yl)acrylaldehyde

Frequently asked questions

What are the approved indications of Basimglurant Sulfate?

Approved indications include: 三叉神经痛, Tuberous sclerosis, 脆性X染色体综合征, Major depressive disorder, Depression.

When does the Basimglurant Sulfate patent expire?

No public expiry year is available for Basimglurant Sulfate yet; this page updates once verified.

How many synthesis routes are recorded for Basimglurant Sulfate?

1 synthesis routes are recorded; the shortest is 6 steps with 69 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Basimglurant Sulfate intermediates?

3 intermediate CAS of Basimglurant Sulfate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Basimglurant Sulfate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-21