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Leflutrozole

Tier C — Watch / trade

Leflutrozole

Novartis
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:Aromatase

Indications (approved):Infertility, 男性不育症, 无精子症, 低促性腺激素性性腺功能减退, Hypogonadism, Endometriosis

Regional status

US
Discontinued
2010-04-15
EU
Phase II
2016-05-12
China
Phase I
2025-09-23
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 1 · Total yield /
LEFLU-001—Leflutrozole143030-47-1API · Leflutrozole
CodeCAS No.Intermediate
LEFLU-001-4,4'-((1H-1,2,4-triazol-3-yl)methylene)dibenzonitrile
Leflutrozole143030-47-14,4'-(fluoro(1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile

Frequently asked questions

What are the approved indications of Leflutrozole?

Approved indications include: Infertility, 男性不育症, 无精子症, 低促性腺激素性性腺功能减退, Hypogonadism, Endometriosis.

When does the Leflutrozole patent expire?

No public expiry year is available for Leflutrozole yet; this page updates once verified.

How many synthesis routes are recorded for Leflutrozole?

1 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Leflutrozole intermediates?

All intermediates in Leflutrozole routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Leflutrozole intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-21