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CAS 105047-45-8

Fmoc-L-Lys-OH

Codes: (I)629485-1-a,(I)629485-1-c

Application context (from source-drug indications)

Basal cell carcinomaRuxotemitideMelanomaRuxotemitideSarcomaRuxotemitideLymphomaRuxotemitideBreast cancerRuxotemitide三阴性乳腺癌Ruxotemitide

Source drugs (routes using this intermediate)

DrugTierExpiry
RuxotemitideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

RuxotemitideOptimised routesteps: 5total yield: /
Fmoc-L-Lys-OH→Resin bound (9-fluorenyl)methyl [(2S)-1,6-diamino-1-oxohexan-2-yl]carbamate→N-[[(9-Fluorenyl)methoxy]carbonyl]-beta-phenyl-L-phenylalanine→Resin bound N-[[(9-fluorenyl)methoxy]carbonyl]-beta-phenyl-L-phenylalanyl-L-lysinamide→N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan→Resin bound N-[[(9-fluorenyl)methoxy]carbonyl]-L-tryptophyl-beta-phenyl-L-phenylalanyl-L-lysinamide→Resin bound N2-[[(9-fluorenyl)methoxy]carbonyl]-L-lysyl-L-tryptophyl-beta-phenyl-L-phenylalanyl-L-lysinamide→Resin bound N2-[[(9-fluorenyl)methoxy]carbonyl]-L-lysyl-L-lysyl-L-tryptophyl-beta-phenyl-L-phenylalanyl-L-lysinamide
RuxotemitideOptimised routesteps: 2total yield: /
Fmoc-L-Lys-OH→Resin bound N-[[(9-fluorenyl)methoxy]carbonyl]-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-beta-phenyl-L-phenylalanyl-L-lysinamide→Resin bound N2-[[(9-fluorenyl)methoxy]carbonyl]-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-beta-phenyl-L-phenylalanyl-L-lysinamide→Resin bound N2-[[(9-fluorenyl)methoxy]carbonyl]-L-lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-beta-phenyl-L-phenylalanyl-L-lysinamide

Intermediates available on this site

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