← Back to patent-cliff list
CAS 106973-36-8
4-Benzyl-5-oxomorpholine-3(R)-carboxylic acid
Codes: (III)448314-2-a
Application context (from source-drug indications)
Hot flushesElinzanetantVasomotor symptomsElinzanetantHR阳性乳腺癌Elinzanetant睡眠障碍ElinzanetantMenopausal symptomsElinzanetantOpioid dependenceElinzanetant
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Elinzanetant | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
N-Benzyl-D-serine→2-Chloranylethanoyl chloride→4-Benzyl-5-oxomorpholine-3(R)-carboxylic acid→[(3S)-4-Benzylmorpholin-3-yl]methanol hydrogen chloride (1/1)→[(3S)-Morpholin-3-yl]methanol hydrogen chloride (1/1)→3-(Benzyloxy)-2(R)-(tert-butoxycarbonylamino)propionic acid→tert-Butyl [(2R)-3-(benzyloxy)-1-[(3S)-3-(hydroxymethyl)morpholin-4-yl]-1-oxopropan-2-yl]carbamate→tert-Butyl [(2S)-1-(benzyloxy)-3-[(3S)-3-(hydroxymethyl)morpholin-4-yl]propan-2-yl]carbamate→tert-Butyl [(2S)-1-(benzyloxy)-3-[(3R)-3-(chloromethyl)morpholin-4-yl]propan-2-yl]carbamate→(2S)-1-(Benzyloxy)-3-[(3R)-3-(chloromethyl)morpholin-4-yl]propan-2-amine→(7S,9aS)-7-[(Benzyloxy)methyl]octahydropyrazino[2,1-c][1,4]oxazine→2-[3,5-Bis(trifluoromethyl)phenyl]-N-[6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-N,2-dimethylpropanamide→N-[6-[(7S,9aS)-7-[(Benzyloxy)methyl]hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide hydrogen chloride (1/2)→N-[6-[(7S,9aS)-7-[(Benzyloxy)methyl]hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | N-Boc-O-Benzyl-D-serine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | N-[6-Chloro-4-(4-fluoro-2-methylp henyl)-3-pyridinyl]-N,a,a-trimethy Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 3-Morpholinemethanol, 4-(phenylmethyl)-, hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | (7S,9aS)-7-((Benzyloxy)methyl)octahydropyrazino[2,1-c][1,4]oxazine dioxalate salt Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 2-(3,5-bis(trifluoroMethyl)phenyl)-2-Methyl propanoic acid Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | ((7S)-octahydropyrazino[2,1-c][1,4]oxazin-7-yl)methanol Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 4-Boc-3-morpholinecarboxylic Acid Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 2-(3,5-bis-trifluoromethylphenyl)-2-methyl-propionyl chloride Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.