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CAS 114133-37-8
(1S)-3-(Methylamino)-1-phenylpropan-1-ol
Codes: (VI)236036-3-a, (V)236036-4-a, (VIII)236036-8-a, (VII)263642-2-a
Application context (from source-drug indications)
分离性焦虑S-fluoxetineAnxietyS-fluoxetineAnxiety disorderS-fluoxetine分离性焦虑R-fluoxetineAnxietyR-fluoxetineAnxiety disorderR-fluoxetine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| S-fluoxetine | Tier C — Watch / trade | - |
| R-fluoxetine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Ethyl (3S)-3-hydroxy-3-phenylpropanoate→1-Phenylpropane-1,3-diol→1-Phenyl-3-(4-toluenesulphonyloxy)propan-1-ol→(1S)-3-{[(4-methylbenzene)sulfonyl]oxy}-1-phenylpropan-1-ol→3-{[(4-methylbenzene)sulfonyl]oxy}-1-phenylpropan-1-one→(1S)-3-(Methylamino)-1-phenylpropan-1-ol→1-Chloro-4-(trifluoromethyl)benzene
3-Phenyl-2-propen-1-ol→[3(R)-Phenyloxiran-2(R)-yl]methanol→(S)-(-)-1-Phenyl-1,3-propanediol→(3S)-3-Hydroxy-3-phenylpropyl methanesulfonate→(1S)-3-(Methylamino)-1-phenylpropan-1-ol→1-Chloro-4-(trifluoromethyl)benzene
Benzaldehyde→Ethynamine→3-Hydroxy-3-phenylpropanenitrile→3-Amino-1-phenylpropan-1-ol→(1S)-3-Amino-1-phenylpropan-1-ol→Carbonochloridic acid methyl ester→Methyl [(3S)-3-hydroxy-3-phenylpropyl]carbamate→(1S)-3-(Methylamino)-1-phenylpropan-1-ol→1-Chloro-4-(trifluoromethyl)benzene→(3S)-3-Phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride→Methyl [(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]carbamate
3-Benzoylpropanoic acid→Methyl 4-oxo-4-phenylbutanoate→(5S)-5-phenyloxolan-2-one→(4S)-4-hydroxy-4-phenylbutanamide→(6S)-6-phenyl-1,3-oxazinan-2-one→(6S)-3-methyl-6-phenyl-1,3-oxazinan-2-one→(1S)-3-(Methylamino)-1-phenylpropan-1-ol→1-Chloro-4-(trifluoromethyl)benzene
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