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CAS 1197996-80-7

1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)

Codes: CBL-0137-009

Source drugs (routes using this intermediate)

DrugTierExpiry
CBL-0137Tier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

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CBL-0137Originator routesteps: 8total yield: 1.04 g (CBL-0137-009)
1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) hydrochloride→2-aminoethan-1-ol→N-(2-hydroxyethyl)-4-nitrobenzenesulfonamide→2-((4-nitrophenyl)sulfonamido)ethyl methanesulfonate→1-((4-nitrophenyl)sulfonyl)aziridine→9H-carbazole→N-(2-(9H-carbazol-9-yl)ethyl)-4-nitrobenzenesulfonamide→N-(2-(3,6-diacetyl-9H-carbazol-9-yl)ethyl)-4-nitrobenzenesulfonamide→1,1'-(9-(2-aminoethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)→1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)

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