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CAS 1261658-58-5

2-ethyl-6-iodobenzoic acid

Codes: Zeprumetostat-002

Application context (from source-drug indications)

Peripheral T-cell lymphomaZeprumetostatLymphomaZeprumetostatT-cell lymphomaZeprumetostatMyelodysplastic syndromeZeprumetostatAcute lymphoblastic leukaemiaZeprumetostatAcute myeloid leukaemiaZeprumetostat

Source drugs (routes using this intermediate)

DrugTierExpiry
ZeprumetostatTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

ZeprumetostatOriginator routesteps: 6total yield: 30.1 mg
2-ethylbenzoic acid→2-ethyl-6-iodobenzoic acid→3,5-dibromo-2-ethyl-6-iodobenzoic acid→1-(prop-2-yn-1-yl)piperidine→6-bromo-5-ethyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylic acid hydrogen chloride→tetrahydro-2H-pyran-4-amine→5-ethyl-2-(piperidin-1-ylmethyl)-6-((tetrahydro-2H-pyran-4-yl)amino)benzofuran-4-carboxylic acid→5-ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-(piperidin-1-ylmethyl)benzofuran-4-carboxylic acid→3-(aminomethyl)-4,6-dimethylpiperidin-2-one hydrogen chloride

Intermediates available on this site

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