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CAS 135297-04-0
(3S,4R)-4-((1S,2R,6R)-7-oxabicyclo[4.1.0]heptan-2-yl)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)azetidin-2-one
Codes: SANFC-022
Application context (from source-drug indications)
Mycobacterium tuberculosis infectionSanfetrinem cilexetilPulmonary tuberculosisSanfetrinem cilexetilBacterial infectionSanfetrinem cilexetil
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Sanfetrinem cilexetil | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2R,3R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl acetate→(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((1R)-3-methoxy-2-oxocyclohexyl)azetidin-2-one→(cyclohex-1-en-1-yloxy)trimethylsilane→(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((R)-2-oxocyclohexyl)azetidin-2-one→N'-((R,E)-2-((2R,3S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl)cyclohexylidene)-4-methylbenzenesulfonohydrazide→(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((S)-cyclohex-2-en-1-yl)azetidin-2-one→(3S,4R)-4-((1S,2R,6R)-7-oxabicyclo[4.1.0]heptan-2-yl)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)azetidin-2-one
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