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CAS 13726-76-6
(tert-butoxycarbonyl)-L-arginine
Codes: LTX-109-001, LTX-109-008
Application context (from source-drug indications)
Staphylococcal infectionVoxvogananCOVID-19VoxvogananHidradenitis suppurativaVoxvoganan脓疱病VoxvogananGram-positive bacterial infectionVoxvogananAtopic dermatitisVoxvoganan
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Voxvoganan | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(tert-butoxycarbonyl)-L-arginine→2-phenylethan-1-amine→tert-butyl (S)-(5-guanidino-1-oxo-1-(phenethylamino)pentan-2-yl)carbamate→(S)-2-amino-5-guanidino-N-phenethylpentanamide→(S)-2-((tert-butoxycarbonyl)amino)-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propanoic acid→tert-butyl ((S)-1-(((S)-5-guanidino-1-oxo-1-(phenethylamino)pentan-2-yl)amino)-1-oxo-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propan-2-yl)carbamate→(S)-2-((S)-2-amino-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propanamido)-5-guanidino-N-phenethylpentanamide→(tert-butoxycarbonyl)-L-arginine→tert-butyl ((6S,9S,12S)-1,17-diamino-1,17-diimino-8,11-dioxo-6-(phenethylcarbamoyl)-9-((2,5,7-tri-tert-butyl-1H-indol-3-yl)methyl)-2,7,10,16-tetraazaheptadecan-12-yl)carbamate
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