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CAS 138108-72-2
tert-butyl (R)-3-(hydroxymethyl)pyrrolidine-1-carboxylate
Codes: DA-8010-002
Application context (from source-drug indications)
Overactive bladderVelufenacinRenal impairmentVelufenacin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Velufenacin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R)-(1-methylpyrrolidin-3-yl)methyl (3'-chloro-4'-fluoro-[1,1'-biphenyl]-2-yl)carbamate→2-bromobenzoic acid→tert-butyl (R)-3-(hydroxymethyl)pyrrolidine-1-carboxylate→tert-butyl (R)-3-((((2-bromophenyl)carbamoyl)oxy)methyl)pyrrolidine-1-carboxylate→(R)-pyrrolidin-3-ylmethyl (2-bromophenyl)carbamate→(R)-(1-methylpyrrolidin-3-yl)methyl (2-bromophenyl)carbamate→(3-chloro-4-fluorophenyl)boronic acid
Intermediates available on this site
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