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CAS 1448307-66-1
1-(2-chloropyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carbaldehyde
Codes: SKI-O-703-003
Application context (from source-drug indications)
Immune thrombocytopenic purpuraCevidoplenibRheumatoid arthritisCevidoplenib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Cevidoplenib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,4-dichloropyrimidine→3-methyl-1H-pyrazole-4-carbaldehyde→1-(2-chloropyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carbaldehyde→(5-amino-1-methyl-1H-indol-3-yl)(cyclopropyl)methanone→1-(2-((3-(cyclopropanecarbonyl)-1-methyl-1H-indol-5-yl)amino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carbaldehyde→(S)-isoxazolidin-4-ol hydrochloride
Intermediates available on this site
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