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CAS 1499168-20-5
9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-amine
Codes: ALISE-012
Application context (from source-drug indications)
Breast cancerAlisertibMetastatic breast cancerAlisertibSmall cell lung cancerAlisertibSolid tumourAlisertibHead and neck squamous cell carcinomaAlisertib横纹肌样瘤Alisertib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Alisertib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(Z)-8-chloro-4-((dimethylamino)methylene)-1-(2-fluoro-6-methoxyphenyl)-3H-benzo[c]azepin-5(4H)-one→guanidine hydrochloride→9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-amine→4-bromo-2-methoxybenzoic acid
Intermediates available on this site
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