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CAS 1564668-60-5
1-(4-(hydroxymethyl)benzyl)pyridin-2(1H)-one
Codes: Sebetralstat-002
Application context (from source-drug indications)
遗传性血管性水肿Sebetralstat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Sebetralstat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(4-(chloromethyl)phenyl)methanol→1-(4-(hydroxymethyl)benzyl)pyridin-2(1H)-one→1-(4-(chloromethyl)benzyl)pyridin-2(1H)-one→methyl 3-(methoxymethyl)-1H-pyrazole-4-carboxylate→methyl 3-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxylate→methyl 5-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxylate→3-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxylic acid→(3-fluoro-4-methoxypyridin-2-yl)methanamine
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