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CAS 1602486-03-2
2-chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridine
Codes: BAY-1251152-003
Application context (from source-drug indications)
Non-Hodgkin lymphomaEnitociclibLymphomaEnitociclibHaematological malignancyEnitociclibNeoplasmEnitociclib里氏综合征EnitociclibChronic lymphocytic leukaemiaEnitociclib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Enitociclib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
((2-((5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone→(4-fluoro-2-methoxyphenyl)boronic acid→2-chloro-5-fluoro-4-iodopyridine→2-chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridine→4-((methylthio)methyl)pyridin-2-amine→5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-(4-((methylthio)methyl)pyridin-2-yl)pyridin-2-amine→2,2,2-trifluoroacetamide→(E)-2,2,2-trifluoro-N-(((2-((5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(methyl)-l4-sulfaneylidene)acetamide
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