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CAS 168828-58-8
(S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
Codes: Sutezolid
Application context (from source-drug indications)
Mycobacterium tuberculosis infectionSutezolidPulmonary tuberculosisSutezolid
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Sutezolid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,2-difluoro-4-nitrobenzene→thiomorpholine→4-(2-fluoro-4-nitrophenyl)thiomorpholine→benzyl (3-fluoro-4-thiomorpholinophenyl)carbamate→(R)-oxiran-2-ylmethyl butyrate→(R)-3-(3-fluoro-4-thiomorpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one→(R)-(3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl 4-methylbenzenesulfonate→(R)-5-(azidomethyl)-3-(3-fluoro-4-thiomorpholinophenyl)oxazolidin-2-one→(S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
benzyl (3-fluoro-4-thiomorpholinophenyl)carbamate→4-chlorobenzaldehyde→(S)-2-(chloromethyl)oxirane→(S,E)-1-chloro-3-((4-chlorobenzylidene)amino)propan-2-ol→(S,Z)-5-(((4-chlorobenzylidene)amino)methyl)-3-(3-fluoro-4-thiomorpholinophenyl)oxazolidin-2-one→(S)-5-(aminomethyl)-3-(3-fluoro-4-thiomorpholinophenyl)oxazolidin-2-one→(S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
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