← Back to patent-cliff list
CAS 1809036-22-3
6-Bromo-8-iodo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine
Codes: (VIII)919110-1-a
Application context (from source-drug indications)
Non-small cell lung cancerDirozalkib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Dirozalkib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Hydroxy-5-methylanisole→2-Methoxy-4-methyl-6-nitrophenol→5-Methyl-3-nitrobenzene-1,2-diol→1,2-Dibromoethane→7-Methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→6-Bromo-7-methyl-5-nitro-2,3-dihydro-1,4-benzodioxine→6-Bromo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→6-Bromo-8-iodo-7-methyl-2,3-dihydro-1,4-benzodioxin-5-amine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→tert-Butyl 4-(8-amino-7-bromo-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)-3,6-dihydropyridine-1(2H)-carboxylate→tert-Butyl 4-(8-amino-6-methyl-2,3-dihydro-1,4-benzodioxin-5-yl)piperidine-1-carboxylate→2,5-Dichloro-N-(2-((1-methylethyl)sulfonyl)phenyl)-4-pyrimidinamine→1-Amino-2-(isopropylsulphonyl)benzene→2,4,5-Trichloropyrimidine→tert-Butyl 4-(8-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-6-methyl-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperidine-1-carboxylate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.