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CAS 1821308-46-6
tert-butyl (1-(4,5-dichloro-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)piperidin-4-yl)carbamate
Codes: CC-90011-005
Application context (from source-drug indications)
NeoplasmPulrodemstatProstate cancerPulrodemstatSmall cell lung cancerPulrodemstatNon-Hodgkin lymphomaPulrodemstatMyeloid leukaemiaPulrodemstat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Pulrodemstat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
perchloropyrimidine→2,5,6-trichloropyrimidin-4-ol→2,5,6-trichloro-3-methylpyrimidin-4(3H)-one→tert-butyl piperidin-4-ylcarbamate→tert-butyl (1-(4,5-dichloro-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)piperidin-4-yl)carbamate→(4-cyano-3-fluorophenyl)boronic acid→tert-butyl (1-(5-chloro-4-(4-cyano-3-fluorophenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)piperidin-4-yl)carbamate→(3-fluoro-4-methoxyphenyl)boronic acid→tert-butyl (1-(4-(4-cyano-3-fluorophenyl)-5-(3-fluoro-4-methoxyphenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)piperidin-4-yl)carbamate
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