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CAS 2867-59-6

(R)-3-aminobutan-1-ol

Codes: Tibremciclib-001

Application context (from source-drug indications)

Breast cancerTibremciclib TartrateMetastatic breast cancerTibremciclib TartrateSolid tumourTibremciclib Tartrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Tibremciclib TartrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Tibremciclib TartrateOptimised routesteps: 4total yield: 1.92 g
(R)-3-aminobutan-1-ol→benzyl (R)-(4-hydroxybutan-2-yl)carbamate→benzyl (R)-(4-oxobutan-2-yl)carbamate→methyl 2-(dimethoxyphosphoryl)acetate→methyl (R,E)-5-(((benzyloxy)carbonyl)amino)hex-2-enoate→(R)-6-methylpiperidin-2-one

Intermediates available on this site

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