CAS 51997-51-4

4-(oxiran-2-ylmethoxy)-9H-carbazole

Codes: Carvedilol-002

Application context (from source-drug indications)

Traumatic brain injuryCarvedilol sulfateHeart failureCarvedilol sulfateEssential hypertensionCarvedilol sulfate

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Carvedilol sulfate	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

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Carvedilol sulfateOptimised routesteps: 2total yield: /

1-((9H-carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol sulfate→2-(2-methoxyphenoxy)ethanamine→4-(oxiran-2-ylmethoxy)-9H-carbazole→1-((9H-carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol

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