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CAS 63257-26-1

4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)tetrahydropyrimidin-2(1H)-one

Codes: TETRA-002

Application context (from source-drug indications)

Non-small cell lung cancerTetrahydrouridineLung cancerTetrahydrouridineSickle cell diseaseTetrahydrouridineMyelodysplastic syndromeTetrahydrouridineAcute myeloid leukaemiaTetrahydrouridineMelanomaTetrahydrouridine

Source drugs (routes using this intermediate)

DrugTierExpiry
TetrahydrouridineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

TetrahydrouridineOriginator routesteps: 2total yield: /
4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5,6-dihydropyrimidin-2(1H)-one→4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)tetrahydropyrimidin-2(1H)-one

Intermediates available on this site

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