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Bivalirudin

Tier C — Watch / trade

Bivalirudin

The Medicines Company
Originator
2000
First approval
-
Expiry (public)
$0.64B ▲
Peak sales
Small molecule
Type

Targets:PT

Brand:Kangio, Angiox, Hirulog (former TM), Angiomax

Indications (approved):Thrombosis, Thromboembolism, Thrombocytopenia, Unstable angina

Regional status

US
Approved
2000-12-15
EU
Withdrawn
China
Approved
2011-08-15
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 18 · Total yield /
BIVA-001—BIVA-002—BIVA-003—BIVA-004—BIVA-005—BIVA-006—BIVA-007—BIVA-008—BIVA-009—BIVA-010—BIVA-011—BIVA-012—BIVA-013—BIVA-014—BIVA-015—BIVA-016—BIVA-017—BIVA-018—API · Bivalirudin
CodeCAS No.Intermediate
BIVA-001--
BIVA-002--
BIVA-003--
BIVA-004--
BIVA-005--
BIVA-006--
BIVA-007--
BIVA-008--
BIVA-009--
BIVA-010--
BIVA-011--
BIVA-012--
BIVA-013--
BIVA-014--
BIVA-015--
BIVA-016--
BIVA-017--
BIVA-018--

Frequently asked questions

What are the approved indications of Bivalirudin?

Approved indications include: Thrombosis, Thromboembolism, Thrombocytopenia, Unstable angina.

When does the Bivalirudin patent expire?

No public expiry year is available for Bivalirudin yet; this page updates once verified.

How many synthesis routes are recorded for Bivalirudin?

1 synthesis routes are recorded; the shortest is 18 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Bivalirudin intermediates?

All intermediates in Bivalirudin routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Bivalirudin intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-04