← Back to patent-cliff list
CAS 861043-74-5
(2E,4E,6Z,8E)-ethyl 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate
Codes: ALIT-009
Application context (from source-drug indications)
Kaposi's sarcomaAlitretinoinHIV infectionAlitretinoinPsoriasisAlitretinoinEczemaAlitretinoin口腔扁平苔藓AlitretinoinBreast cancerAlitretinoin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Alitretinoin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(2,6,6-trimethylcyclohex-1-en-1-yl)acetaldehyde→(E)-2-(2,6,6-trimethylcyclohex-1-en-1-yl)vinyl trifluoromethanesulfonate→(Z)-3-(tributylstannyl)but-2-en-1-ol→(2Z,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dien-1-ol→(2Z,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienal→1,3,3-trimethyl-2-((1E,3Z)-3-methylhexa-1,3-dien-5-yn-1-yl)cyclohex-1-ene→tributyl((1E,3Z,5E)-4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hexa-1,3,5-trien-1-yl)stannane→(E)-ethyl 3-(((trifluoromethyl)sulfonyl)oxy)but-2-enoate→(2E,4E,6Z,8E)-ethyl 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate
(2E,4E,6Z,8E)-ethyl 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate→2,2,6-trimethylcyclohexanone→(2,2,6-trimethylcyclohexylidene)hydrazine→2-iodo-1,3,3-trimethylcyclohex-1-ene→dimethyl (2,6,6-trimethylcyclohex-1-en-1-yl)boronate→(2E,4E,6Z,8E)-ethyl 9-iodo-3,7-dimethylnona-2,4,6,8-tetraenoate
(2Z,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienal→(2E,4E,6Z,8E)-ethyl 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate→(E)-2-(but-1-en-3-yn-1-yl)-1,3,3-trimethylcyclohex-1-ene→(E)-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-4-en-2-ynenitrile→(2Z,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienenitrile→ethyl (E)-4-(diethoxyphosphoryl)-3-methylbut-2-enoate→ethyl (E)-4-(diethoxyphosphoryl)-3-methylbut-2-enoate
(2E,4E,6Z,8E)-ethyl 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate→ethyl (E)-4-(diethoxyphosphoryl)-3-methylbut-2-enoate→2,6,6-trimethylcyclohex-1-enecarbaldehyde→2,6,6-trimethylcyclohexa-1,3-dienecarbaldehyde→ethyl 3-methylbut-2-enoate→4-methyl-6-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)-5,6-dihydro-2H-pyran-2-one→(2Z,4E)-3-methyl-5-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)penta-2,4-dienal→(2E,4E,6Z,8E)-ethyl 3,7-dimethyl-9-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)nona-2,4,6,8-tetraenoate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.