Pidnarulex
Tier C — Watch / tradePidnarulex
Targets：POLR2, POLR1A
Indications (approved)：Colorectal cancer, Solid tumour, Burkitt淋巴瘤, B-cell lymphoma, Lymphoma, HR阳性乳腺癌, Breast cancer, 三阴性乳腺癌
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CX-5461 | 1138549-36-6 | 2-(4-methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide |
| CX-5461-001 | 38496-18-3 | 2,6-dichloronicotinic acid |
| CX-5461-002 | 58584-83-1 | 2,6-dichloronicotinoyl chloride |
| CX-5461-003 | 29182-42-1 | ethyl 2-(benzo[d]thiazol-2-yl)acetate |
| CX-5461-004 | 881633-93-8 | ethyl 2-chloro-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxylate |
| CX-5461-005 | 4318-37-0 | 1-methyl-1,4-diazepane |
| CX-5461-006 | 1138555-04-0 | ethyl 2-(4-methyl-1,4-diazepan-1-yl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxylate |
| CX-5461-007 | 132664-85-8 | (5-methylpyrazin-2-yl)methanamine |
Frequently asked questions
What are the approved indications of Pidnarulex?
Approved indications include: Colorectal cancer, Solid tumour, Burkitt淋巴瘤, B-cell lymphoma, Lymphoma, HR阳性乳腺癌, Breast cancer, 三阴性乳腺癌.
When does the Pidnarulex patent expire?
No public expiry year is available for Pidnarulex yet; this page updates once verified.
How many synthesis routes are recorded for Pidnarulex?
1 synthesis routes are recorded; the shortest is 4 steps with 24.1 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Pidnarulex intermediates?
All intermediates in Pidnarulex routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Pidnarulex intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-01