MK-2206
Tier C — Watch / tradeMK-2206
Targets：AKT1
Indications (approved)：Peritoneal cancer, Prostate cancer, Small cell lung cancer, 胸腺瘤, Non-small cell lung cancer, 皮肤黑色素瘤, Solid tumour, Renal cell carcinoma
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| MK-2206-001 | 50921-39-6 | 1-(4-chlorophenyl)cyclobutane-1-carboxylic acid |
| MK-2206-002 | 1032349-96-4 | tert-butyl (1-(4-chlorophenyl)cyclobutyl)carbamate |
| MK-2206-003 | 1032349-97-5 | tert-butyl (1-(4-cyanophenyl)cyclobutyl)carbamate |
| MK-2206-004 | 1032349-98-6 | tert-butyl (1-(4-(2-phenylacetyl)phenyl)cyclobutyl)carbamate |
| MK-2206-005 | 893423-62-6 | tert-butyl (2-chloro-3-formylpyridin-4-yl)carbamate |
| MK-2206-006 | 1032349-99-7 | tert-butyl (1-(4-(5-chloro-3-phenyl-1,6-naphthyridin-2-yl)phenyl)cyclobutyl)carbamate |
| MK-2206-007 | 1032350-00-7 | tert-butyl (1-(4-(5-hydrazineyl-3-phenyl-1,6-naphthyridin-2-yl)phenyl)cyclobutyl)carbamate |
| MK-2206-008 | 1032350-03-0 | tert-butyl (1-(4-(3-hydroxy-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-8-yl)phenyl)cyclobutyl)carbamate |
Frequently asked questions
What are the approved indications of MK-2206?
Approved indications include: Peritoneal cancer, Prostate cancer, Small cell lung cancer, 胸腺瘤, Non-small cell lung cancer, 皮肤黑色素瘤, Solid tumour, Renal cell carcinoma.
When does the MK-2206 patent expire?
No public expiry year is available for MK-2206 yet; this page updates once verified.
How many synthesis routes are recorded for MK-2206?
1 synthesis routes are recorded; the shortest is 7 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy MK-2206 intermediates?
All intermediates in MK-2206 routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for MK-2206 intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-21