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CAS 50921-39-6
1-(4-chlorophenyl)cyclobutane-1-carboxylic acid
Codes: MK-2206-001
Application context (from source-drug indications)
Peritoneal cancerMK-2206Prostate cancerMK-2206Small cell lung cancerMK-2206胸腺瘤MK-2206Non-small cell lung cancerMK-2206皮肤黑色素瘤MK-2206
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| MK-2206 | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(4-chlorophenyl)cyclobutane-1-carboxylic acid→tert-butyl (1-(4-chlorophenyl)cyclobutyl)carbamate→tert-butyl (1-(4-cyanophenyl)cyclobutyl)carbamate→tert-butyl (1-(4-(2-phenylacetyl)phenyl)cyclobutyl)carbamate→tert-butyl (2-chloro-3-formylpyridin-4-yl)carbamate→tert-butyl (1-(4-(5-chloro-3-phenyl-1,6-naphthyridin-2-yl)phenyl)cyclobutyl)carbamate→tert-butyl (1-(4-(5-hydrazineyl-3-phenyl-1,6-naphthyridin-2-yl)phenyl)cyclobutyl)carbamate→tert-butyl (1-(4-(3-hydroxy-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-8-yl)phenyl)cyclobutyl)carbamate
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