Lenumlostat hydrochloride
Tier C — Watch / tradeLenumlostat hydrochloride
Targets：LOXL2
Indications (approved)：Myelofibrosis, Essential thrombocythaemia, Polycythaemia vera
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PAT-1251-001 | 1196155-38-0 | 2-chloro-6-(trifluoromethyl)isonicotinonitrile |
| PAT-1251-002 | 19438-10-9 | methyl 3-hydroxybenzoate |
| PAT-1251-003 | 2007887-91-2 | methyl 3-((4-cyano-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoate |
| PAT-1251-004 | 2007887-92-3 | methyl 3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoate |
| PAT-1251-005 | 2007887-93-4 | methyl 3-((4-(((tert-butoxycarbonyl)amino)methyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoate |
| PAT-1251-006 | 2007887-67-2 | 3-((4-(((tert-butoxycarbonyl)amino)methyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoic acid |
| PAT-1251-007 | 2006333-41-9 | (3S,4S)-4-fluoropyrrolidin-3-ol hydrochloride |
| PAT-1251-008 | 2099683-12-0 | tert-butyl ((2-(3-(3-fluoro-4-hydroxypyrrolidine-1-carbonyl)phenoxy)-6-(trifluoromethyl)pyridin-4-yl)methyl)carbamate |
| PAT-1251-009 | 2098884-52-5 | (3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone |
Frequently asked questions
What are the approved indications of Lenumlostat hydrochloride?
Approved indications include: Myelofibrosis, Essential thrombocythaemia, Polycythaemia vera.
When does the Lenumlostat hydrochloride patent expire?
No public expiry year is available for Lenumlostat hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Lenumlostat hydrochloride?
1 synthesis routes are recorded; the shortest is 7 steps with 89 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Lenumlostat hydrochloride intermediates?
All intermediates in Lenumlostat hydrochloride routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Lenumlostat hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-07