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Oxaliplatin

Tier B — Position early

Oxaliplatin

Sanofi
Originator
1996
First approval
-
Expiry (public)
$1.49B ▲
Peak sales
Small molecule
Type

Targets:DNA

Brand:Dacplat, Elplat, Dacotin, L-platin, Transplatin, Foloxatine, Eloxatine, Eloxatin

Indications (approved):Intestinal neoplasm, Gastric cancer, Pancreatic cancer, Colorectal cancer, Colon cancer

Regional status

US
Withdrawn
EU
Approved
1996-01-01
China
Approved
2000-01-01
Japan
Approved
2009-08-20

Synthetic routes & intermediates5 routes

Originator routes × 1Optimised (non-patent) × 4Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield 20 g
OXALI-00120439-47-8OXALI-00238780-40-4OXALI-0036153-56-6API · Oxaliplatin
CodeCAS No.Intermediate
OXALI-00120439-47-8(1R,2R)-cyclohexane-1,2-diamine
OXALI-00238780-40-4-
OXALI-0036153-56-6oxalic acid
OptimisedRoute 2Steps 3 · Total yield /
OXALI-00120439-47-8OXALI-00466845-32-7OXALI-00566900-68-3OXALI-0066487-48-5API · Oxaliplatin
CodeCAS No.Intermediate
OXALI-00120439-47-8(1R,2R)-cyclohexane-1,2-diamine
OXALI-00466845-32-7-
OXALI-00566900-68-3-
OXALI-0066487-48-5potassium oxalate
OptimisedRoute 3Steps 2 · Total yield 2.9 g
OXALI-00120439-47-8OXALI-00716921-30-5OXALI-00814244-64-5OXALI-00914244-64-5API · Oxaliplatin
CodeCAS No.Intermediate
OXALI-00120439-47-8(1R,2R)-cyclohexane-1,2-diamine
OXALI-00716921-30-5-
OXALI-00814244-64-5-
OXALI-00914244-64-5-
OptimisedRoute 4Steps 3 · Total yield 29.87 g
OXALI-00120439-47-8OXALI-00466845-32-7OXALI-01094042-08-7OXALI-01162-76-0API · Oxaliplatin
CodeCAS No.Intermediate
OXALI-00120439-47-8(1R,2R)-cyclohexane-1,2-diamine
OXALI-00466845-32-7-
OXALI-01094042-08-7-
OXALI-01162-76-0sodium oxalate
OptimisedRoute 5Steps 2 · Total yield 2.8 g
OXALI-00120439-47-8OXALI-0036153-56-6OXALI-01289955-85-1API · Oxaliplatin
CodeCAS No.Intermediate
OXALI-00120439-47-8(1R,2R)-cyclohexane-1,2-diamine
OXALI-0036153-56-6oxalic acid
OXALI-01289955-85-1-

Frequently asked questions

What are the approved indications of Oxaliplatin?

Approved indications include: Intestinal neoplasm, Gastric cancer, Pancreatic cancer, Colorectal cancer, Colon cancer.

When does the Oxaliplatin patent expire?

No public expiry year is available for Oxaliplatin yet; this page updates once verified.

How many synthesis routes are recorded for Oxaliplatin?

5 synthesis routes are recorded; the shortest is 2 steps with 20 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Oxaliplatin intermediates?

All intermediates in Oxaliplatin routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Oxaliplatin intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-04