Obicetrapib
Tier C — Watch / tradeObicetrapib
Targets：CETP
Indications (approved)：Myocardial infarction, Atherosclerosis, Hypercholesterolaemia, Hyperlipoproteinaemia type II, 代谢病, 高脂蛋白血症, 先天性代谢缺陷病, Dyslipidaemia
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| OBIC-001 | 402-43-7 | 1-bromo-4-(trifluoromethyl)benzene |
| OBIC-002 | 131347-76-7 | (R)-3-aminopentanoic acid |
| OBIC-003 | 474645-90-4 | (R)-3-((4-(trifluoromethyl)phenyl)amino)pentanoic acid |
| OBIC-004 | 952582-00-2 | (R)-2-ethyl-6-(trifluoromethyl)-2,3-dihydroquinolin-4(1H)-one |
| OBIC-005 | 952581-99-6 | (R,E)-2-ethyl-6-(trifluoromethyl)-2,3-dihydroquinolin-4(1H)-one oxime |
| Code | CAS No. | Intermediate |
|---|---|---|
| OBIC-006 | 455-14-1 | 4-(trifluoromethyl)aniline |
| OBIC-007 | - | N-(2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl)formamide |
| OBIC-008 | 1878192-73-4 | 2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-amine |
| OBIC-009 | 71607-32-4 | (2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinic acid hydrate |
| OBIC-010 | - | (2R,4S)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-amine (2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate |
Frequently asked questions
What are the approved indications of Obicetrapib?
Approved indications include: Myocardial infarction, Atherosclerosis, Hypercholesterolaemia, Hyperlipoproteinaemia type II, 代谢病, 高脂蛋白血症, 先天性代谢缺陷病, Dyslipidaemia.
When does the Obicetrapib patent expire?
No public expiry year is available for Obicetrapib yet; this page updates once verified.
How many synthesis routes are recorded for Obicetrapib?
2 synthesis routes are recorded; the shortest is 4 steps with 375 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Obicetrapib intermediates?
All intermediates in Obicetrapib routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Obicetrapib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-06