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CAS 1878192-73-4

2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-amine

Codes: OBIC-008

Application context (from source-drug indications)

Myocardial infarctionObicetrapibAtherosclerosisObicetrapibHypercholesterolaemiaObicetrapibHyperlipoproteinaemia type IIObicetrapib代谢病Obicetrapib高脂蛋白血症Obicetrapib

Source drugs (routes using this intermediate)

DrugTierExpiry
ObicetrapibTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

ObicetrapibOptimised routesteps: 4total yield: 2.58 g
4-(trifluoromethyl)aniline→N-(2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl)formamide→2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-amine→(2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinic acid hydrate→(2R,4S)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-amine (2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate

Intermediates available on this site

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