Napazimone
Tier C — Watch / tradeNapazimone
Targets：NAD(Nicotinamide adenine dinucleotide)
Indications (approved)：线粒体疾病, 线粒体肌病, 线粒体脑肌症候群
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| KL-1333 | 1800405-30-4 | 2-isopropyl-3H-naphtho[1,2-d]imidazole-4,5-dione |
| KL-1333-001 | 5959-56-8 | 4-aminonaphthalen-1-ol hydrochloride |
| KL-1333-002 | 97-72-3Available | isobutyric anhydride |
| KL-1333-003 | 1624260-34-9 | 4-isobutyramidonaphthalen-1-yl isobutyrate |
| KL-1333-004 | 1800406-29-4 | 4-isobutyramido-3-nitronaphthalen-1-yl isobutyrate |
| KL-1333-005 | 1800406-30-7 | N-(2-amino-4-hydroxynaphthalen-1-yl)isobutyramide |
| KL-1333-006 | 1800406-31-8 | 2-isopropyl-3H-naphtho[1,2-d]imidazol-5-ol |
Frequently asked questions
What are the approved indications of Napazimone?
Approved indications include: 线粒体疾病, 线粒体肌病, 线粒体脑肌症候群.
When does the Napazimone patent expire?
No public expiry year is available for Napazimone yet; this page updates once verified.
How many synthesis routes are recorded for Napazimone?
1 synthesis routes are recorded; the shortest is 5 steps with 47 mg (KL-1333) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Napazimone intermediates?
1 intermediate CAS of Napazimone are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Napazimone intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-21