CAS 1800406-30-7

N-(2-amino-4-hydroxynaphthalen-1-yl)isobutyramide

Codes: KL-1333-005

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Napazimone	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

NapazimoneOriginator routesteps: 5total yield: 47 mg (KL-1333)

2-isopropyl-3H-naphtho[1,2-d]imidazole-4,5-dione→4-aminonaphthalen-1-ol hydrochloride→isobutyric anhydride→4-isobutyramidonaphthalen-1-yl isobutyrate→4-isobutyramido-3-nitronaphthalen-1-yl isobutyrate→N-(2-amino-4-hydroxynaphthalen-1-yl)isobutyramide→2-isopropyl-3H-naphtho[1,2-d]imidazol-5-ol

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