Butylphthalide

Tier C — Watch / trade

Butylphthalide

CSPC Ouyi Pharmaceutical Co., Ltd.

Originator

2002

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：Tandem pore domain potassium channels

Indications (approved)：Ischaemic stroke

Regional status

China

Approved

2002-09-30

Japan

Synthetic routes & intermediates2 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 1

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 2Steps 3 · Total yield 32.1 g

BUTY-004109-65-9BUTY-005693-03-8BUTY-0067468-67-9BUTY-007—API · Butylphthalide

Code	CAS No.	Intermediate
BUTY-004	109-65-9	1-bromobutane
BUTY-005	693-03-8	butylmagnesium bromide
BUTY-006	7468-67-9	2-formylbenzonitrile
BUTY-007	-	2-(1-hydroxypentyl)benzonitrile

ProcessRoute 1Steps 2 · Total yield 42.5 Kg

BUTY-00185-44-9BUTY-0022082-59-9BUTY-003551-08-6Butylphthalide6066-49-5API · Butylphthalide

Code	CAS No.	Intermediate
BUTY-001	85-44-9 Available	isobenzofuran-1,3-dione
BUTY-002	2082-59-9	pentanoic anhydride
BUTY-003	551-08-6	(Z)-3-butylideneisobenzofuran-1(3H)-one
Butylphthalide	6066-49-5	-

Frequently asked questions

What are the approved indications of Butylphthalide?

Approved indications include: Ischaemic stroke.

When does the Butylphthalide patent expire?

No public expiry year is available for Butylphthalide yet; this page updates once verified.

How many synthesis routes are recorded for Butylphthalide?

2 synthesis routes are recorded; the shortest is 2 steps with 42.5 Kg total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Butylphthalide intermediates?

1 intermediate CAS of Butylphthalide are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Butylphthalide intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-04