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Caffeine Citrate

Tier C — Watch / trade

Caffeine Citrate

Hikma Pharmaceuticals Plc
Originator
1999
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:ADORA2, ADORA1

Brand:Peyona, Nymusa, Gencebok, Cafcit

Indications (approved):呼吸暂停

Regional status

US
Approved
1999-09-21
EU
Approved
2009-07-02
China
Approved
2013-01-22
Japan
No progress
2011-08-01

Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 1 · Total yield 257.15g(Caffeine Citrate-002)
Caffeine Citrate-001—Caffeine Citrate-002—API · Caffeine Citrate
CodeCAS No.Intermediate
Caffeine Citrate-001-(5E)-5-(Hydroxyimino)-6-imino-1,3-dimethyldihydropyrimidine-2,4(1H,3H)-dione hydrochloride
Caffeine Citrate-002-5,6-Diamino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride

Frequently asked questions

What are the approved indications of Caffeine Citrate?

Approved indications include: 呼吸暂停.

When does the Caffeine Citrate patent expire?

No public expiry year is available for Caffeine Citrate yet; this page updates once verified.

How many synthesis routes are recorded for Caffeine Citrate?

1 synthesis routes are recorded; the shortest is 1 steps with 257.15g(Caffeine Citrate-002) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Caffeine Citrate intermediates?

All intermediates in Caffeine Citrate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Caffeine Citrate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-04