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CAS 1281566-89-9
2-(3-chlorophenyl)-6-(trifluoromethyl)pyrimidin-4(3H)-one
Codes: BPN-14770-005
Application context (from source-drug indications)
脆性X染色体综合征Zatolmilast乔丹综合征ZatolmilastHepatic function declineZatolmilastRenal impairmentZatolmilastAlzheimer's diseaseZatolmilastDepressionZatolmilast
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Zatolmilast | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-chlorobenzonitrile→ethyl 3-chlorobenzimidate hydrochloride→3-chlorobenzimidamide→ethyl 4,4,4-trifluoro-3-oxobutanoate→2-(3-chlorophenyl)-6-(trifluoromethyl)pyrimidin-4(3H)-one→4-chloro-2-(3-chlorophenyl)-6-(trifluoromethyl)pyrimidine→2-(4-aminophenyl)acetamide→BPN-14770
Intermediates available on this site
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