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CAS 1334167-66-6
4-(2-fluoro-4-nitrophenyl)-1-methyl-1,4,5,6-tetrahydro-1,2,4-triazine
Codes: DELPA-016
Application context (from source-drug indications)
Non-tuberculous mycobacterial infectionDelpazolidPulmonary tuberculosisDelpazolidMycobacterium tuberculosis infectionDelpazolidStaphylococcal infectionDelpazolid
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Delpazolid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,2-difluoro-4-nitrobenzene→2-((2-fluoro-4-nitrophenyl)amino)ethan-1-ol→(R)-oxiran-2-ylmethyl pivalate→1-(2-fluoro-4-nitrophenyl)aziridine→2-fluoro-N-(2-(1-methylhydrazineyl)ethyl)-4-nitroaniline→4-(2-fluoro-4-nitrophenyl)-1-methyl-1,4,5,6-tetrahydro-1,2,4-triazine→3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)aniline→ethyl (3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)carbamate→(R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
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