Delpazolid
Tier C — Watch / tradeDelpazolid
Targets：50S ribosomal subunit
Indications (approved)：Non-tuberculous mycobacterial infection, Pulmonary tuberculosis, Mycobacterium tuberculosis infection, Staphylococcal infection
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| DELPA-001 | 369-34-6 | 1,2-difluoro-4-nitrobenzene |
| DELPA-002 | 509151-97-7 | 2-((2-fluoro-4-nitrophenyl)amino)ethan-1-ol |
| DELPA-003 | 1219708-10-7 | tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(2-fluoro-4-nitrophenyl)carbamate |
| DELPA-004 | 1219708-12-9 | tert-butyl (4-amino-2-fluorophenyl)(2-((tert-butyldimethylsilyl)oxy)ethyl)carbamate |
| DELPA-005 | 1219708-13-0 | tert-butyl (4-(((benzyloxy)carbonyl)amino)-2-fluorophenyl)(2-((tert-butyldimethylsilyl)oxy)ethyl)carbamate |
| DELPA-006 | 128969-92-6 | (R)-oxiran-2-ylmethyl pivalate |
| DELPA-007 | 1219708-14-1 | tert-butyl (R)-(2-((tert-butyldimethylsilyl)oxy)ethyl)(2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenyl)carbamate |
| DELPA-008 | 1219708-32-3 | (R)-(3-(4-((tert-butoxycarbonyl)(2-((tert-butyldimethylsilyl)oxy)ethyl)amino)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl benzoate |
| DELPA-009 | 1219708-33-4 | (R)-(3-(3-fluoro-4-((2-hydroxyethyl)amino)phenyl)-2-oxooxazolidin-5-yl)methyl benzoate |
| DELPA-010 | 1321533-83-8 | (R)-(3-(3-fluoro-4-((2-((methylsulfonyl)oxy)ethyl)amino)phenyl)-2-oxooxazolidin-5-yl)methyl benzoate |
| DELPA-011 | 1321533-84-9 | (R)-(3-(3-fluoro-4-((2-hydrazineylethyl)amino)phenyl)-2-oxooxazolidin-5-yl)methyl benzoate |
| DELPA-012 | 1219707-37-5 | (R)-4-(2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenyl)-5,6-dihydro-1,2,4-triazine-1(4H)-carbaldehyde |
| DELPA-013 | 1219707-38-6 | (R)-3-(4-(5,6-dihydro-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one |
| Delpazolid | 1219707-39-7 | (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one |
| Code | CAS No. | Intermediate |
|---|---|---|
| DELPA-001 | 369-34-6 | 1,2-difluoro-4-nitrobenzene |
| DELPA-002 | 509151-97-7 | 2-((2-fluoro-4-nitrophenyl)amino)ethan-1-ol |
| DELPA-006 | 128969-92-6 | (R)-oxiran-2-ylmethyl pivalate |
| DELPA-014 | 1334167-74-6 | 1-(2-fluoro-4-nitrophenyl)aziridine |
| DELPA-015 | 1334167-62-2 | 2-fluoro-N-(2-(1-methylhydrazineyl)ethyl)-4-nitroaniline |
| DELPA-016 | 1334167-66-6 | 4-(2-fluoro-4-nitrophenyl)-1-methyl-1,4,5,6-tetrahydro-1,2,4-triazine |
| DELPA-017 | 1334167-69-9 | 3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)aniline |
| DELPA-018 | 1334167-72-4 | ethyl (3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)carbamate |
| Delpazolid | 1219707-39-7 | (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one |
Frequently asked questions
What are the approved indications of Delpazolid?
Approved indications include: Non-tuberculous mycobacterial infection, Pulmonary tuberculosis, Mycobacterium tuberculosis infection, Staphylococcal infection.
When does the Delpazolid patent expire?
No public expiry year is available for Delpazolid yet; this page updates once verified.
How many synthesis routes are recorded for Delpazolid?
2 synthesis routes are recorded; the shortest is 7 steps with 22.5 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Delpazolid intermediates?
All intermediates in Delpazolid routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Delpazolid intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-09