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CAS 1375257-37-6
(S)-3-((R)-3-hydroxy-3-phenylpropanoyl)-4-isopropyl-1-((R)-1-phenylethyl)imidazolidin-2-one
Codes: R-fluoxetine-009
Application context (from source-drug indications)
分离性焦虑R-fluoxetineAnxietyR-fluoxetineAnxiety disorderR-fluoxetine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| R-fluoxetine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-2-amino-3-methylbutanoic acid→(tert-butoxycarbonyl)-L-valine→(R)-1-phenylethan-1-amine→tert-butyl ((S)-3-methyl-1-oxo-1-(((R)-1-phenylethyl)amino)butan-2-yl)carbamate→(S)-2-amino-3-methyl-N-((R)-1-phenylethyl)butanamide→(S)-3-methyl-N1-((R)-1-phenylethyl)butane-1,2-diamine→(S)-4-isopropyl-1-((R)-1-phenylethyl)imidazolidin-2-one→(S)-3-acetyl-4-isopropyl-1-((R)-1-phenylethyl)imidazolidin-2-one→(S)-3-((R)-3-hydroxy-3-phenylpropanoyl)-4-isopropyl-1-((R)-1-phenylethyl)imidazolidin-2-one→(R)-3-hydroxy-N-methyl-3-phenylpropanamide→(R)-3-(methylamino)-1-phenylpropan-1-ol→1-fluoro-4-(trifluoromethyl)benzene→R-fluoxetine
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