CAS 1480542-41-3

(1R,2S)-1-(3,5-diiodophenyl)-2-nitropropan-1-ol

Codes: ANAC-043

Application context (from source-drug indications)

HypercholesterolaemiaAnacetrapibCardiac and vascular disordersAnacetrapibDyslipidaemiaAnacetrapibAtherosclerosisAnacetrapibHyperlipoproteinaemia type IIAnacetrapibHomozygous familial hypercholesterolaemiaAnacetrapib

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Anacetrapib	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

AnacetrapibOptimised routesteps: 4total yield: 85.00 mg

(4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyloxazolidin-2-one→nitroethane→2'-(chloromethyl)-4-fluoro-5-isopropyl-2-methoxy-4'-(trifluoromethyl)-1,1'-biphenyl→3,5-diiodobenzaldehyde→(1R,2S)-1-(3,5-diiodophenyl)-2-nitropropan-1-ol→(4S,5R)-5-(3,5-diiodophenyl)-4-methyloxazolidin-2-one

Intermediates available on this site

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